I. Core Function: Ensure the accuracy and safety of micropipetting

Precise liquid transfer: The pipette tip, through a tight fit with the pipette, forms a closed space, and the liquid is drawn up and discharged by the pressure change of the pipette. Its inner wall smoothness, volume accuracy and other designs can minimize liquid residue to the greatest extent and ensure that the transfer volume is consistent with the set value. Especially in microoperations at the μL or even nL level (such as PCR reactions in molecular biology experiments, reagent addition in cell culture, etc.), accuracy is of vital importance.

Avoid cross-contamination: The pipette tips are disposable consumables (in special scenarios, they can be sterilized and reused repeatedly, but strict handling is required). Replacing them with new tips each time a pipette is performed can completely prevent cross-contamination between different samples or reagents, which is the fundamental guarantee for the reliability of laboratory results.

Protecting the pipette: The pipette tip is in direct contact with the liquid, which can prevent samples or reagents from contaminating the precision components inside the pipette (such as pistons, sealing rings, etc.), thereby extending the service life of the pipette

Ii. Design Features: Details determine accuracy

Material: The mainstream material is polypropylene (PP), which features strong chemical inertness (resistant to most acids, alkalis and organic solvents), high transparency (easy to observe the liquid level), and moderate flexibility (can closely adhere to the pipette tip). Some special pipette tips are added with conductive materials (for automated pipetting systems to prevent static interference) or low-adsorption coatings (to reduce the residue of viscous liquids such as proteins and nucleic acids).

Structural details

The suction end: The tip design is diverse, including pointed tips (suitable for reaching the bottom of microcentrifuge tubes), round tips (reducing shear force on sensitive samples such as cells), and serrated shapes (facilitating liquid pouring), etc. Moreover, the edges are smooth to prevent air bubbles or liquid adhesion during suction.

The connection end: The inner wall has grooves or patterns that are suitable for different brands of pipettes, ensuring the "airtightness" with the pipette - this is the key to precise pipetting. If it does not fit tightly, it will lead to insufficient pipetting volume or leakage.

Scale marking: The outer walls of some large-capacity pipette tips (such as 1mL, 5mL) are marked with scales to assist in quickly determining the volume to be removed.